Selected Publications

(See the full list at Google Scholar)

Feng, Y.-C. A., Lin, M.-C., Tseng, C.-H., Wu, C.-S., Tsai, M.-H.*, Wang, S.-H.* (2026). Paternal valproate exposure and offspring neurodevelopmental outcomes. Neurology, 107(6), e218375.

Ke, Y.-S., Tsai, M.-H., Ho, C.-R., Chou, C.-Y., Chen, H.-H., Stevelink, R., ..., Sung, S.-F., Lee, M.-C., Chen, J.-T., & Feng, Y.-C. A.* (2026). Variability in epilepsy polygenic risk prediction across Taiwanese population and clinical cohorts. Epilepsia.

Liu, R., Chen, T.-T., Xia, Y., Lin, S.-C., Ge, T., Chen, C.-Y.*, Feng, Y.-C. A.*, Huang, H.*, & Lin, Y.-F.* (2026). Genetic regulation of methylation across East Asian and European populations. Nature Communications, 17(1), 2616.

Wang, L.-H., Shih, M.-Y., Lin, Y.-F., Kuo, P.-H., & Feng, Y.-C. A.* (2025). Polygenic dissection of treatment-resistant depression with proxy phenotypes in the UK Biobank. Journal of Affective Disorders, 381, 350-359.

Feng, Y.-C. A., Chen, W. J., Lin, M. C., Hsu, J. S., Cheng, C. F., Liu, C. H., Hwu, H. G., Huang, Y. T., Lu, T. P., & Wang, S. H. (2025). Paternal age, de novo mutation, and age at onset among co-affected schizophrenia sib-pairs: whole-genome sequencing in multiplex families. Molecular Psychiatry, 30(8), 3560-3567.

Chen, C. Y.*, Chen, T. T., Feng, Y.-C. A.*, Yu, M., Lin, S. C., Longchamps, R., Wang, S. H., Hsu, Y. H., Yang, H. I., Kuo, P. H., Daly, M. J., Chen, W. J., Huang, H.*, Ge, T.*, & Lin, Y. F.* (2023). Analysis across Taiwan Biobank, Biobank Japan and UK Biobank identifies hundreds of novel loci for 36 quantitative traits. Cell Genomics, 3(12):100436.

Campos, A. I., Namba, S., Lin, S. C., Nam, K., Sidorenko, J., Wang, H., Kamatani, Y., Biobank Japan Project, Wang, L. H., Lee, S., Lin, Y. F., Feng, Y.-C. A., Okada, Y., Visscher, P., & Yengo, L. (2023). Boosting the power of genome-wide association studies within and across ancestries by using polygenic scores. Nature Genetics, 55, 1769–1776.

Feng, Y.-C. A.*, Chen, C. Y., Chen, T. T., Kuo, P. H., Hsu, Y. H., Yang, H. I., Chen, W. J., Shen, C. Y., Ge, T., Huang, H., Lin, Y. F.* (2022). Taiwan Biobank: a rich biomedical research database of the Taiwanese population. Cell Genomics, 2(11): 100197.

Feng, Y.-C. A.*, Stanaway, I. B., Connolly, J. J., Denny, J. C., Luo, Y., Weng, C., Wei, W.-Q., Weiss, S. T., Karlson, E. W., & Smoller, J. W.* (2022). Psychiatric manifestations of rare variation in medically actionable genes: a PheWAS approach. BMC Genomics, 23(1), 385.

Ruan, Y., Lin, Y.-F., Feng, Y.-C. A., Chen, C.-Y., Lam, M., Guo, Z., Stanley Global Asia Initiatives, He, L., Sawa, A., Martin, A. R., Qin, S., Huang, H., & Ge, T. (2022). Improving polygenic prediction in ancestrally diverse populations. Nature Genetics, 54(5), 573–580.

COVID-19 Host Genetics Initiative (2021). Mapping the human genetic architecture of COVID-19. Nature, 600(7889), 472-477.

Feng, Y.-C. A.*, Guo, Y., Pain, L., Lathrop, G. M., Laprise, C., Moffatt, M. F., Cookson, W. O., & Liang, L.* (2021). Estimating cell-type-specific DNA methylation effects in heterogeneous cellular populations. Epigenomics, 13(2), 87–97.

Lee, P. H., Feng, Y.-C. A., & Smoller, J. W. (2021). Pleiotropy and Cross-Disorder Genetics Among Psychiatric Disorders. Biological Psychiatry, 89(1), 20-31.

Lee, P. H., Anttila, V., Won, H., Feng, Y.-C. A., Rosenthal, J., Zhu, Z., ..., Smoller, J. W. (Cross-Disorder Group of the Psychiatric Genomics Consortium) (2019). Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. Cell, 179(7), 1469-1482.e11.

Feng, Y.-C. A., Howrigan, D. P., Abbott, L. E., Tashman, K., Cerrato, F., Singh, T., ..., Daly, M. J., Lander, E. S., Lowenstein, D. H., Goldstein, D., Lerche, H., Berkovic, S. F., & Neale, B. M. (Epi25 Collaborative) (2019). Ultra-Rare Genetic Variation in the Epilepsies: A Whole-Exome Sequencing Study of 17,606 Individuals. The American Journal of Human Genetics, 105(2), 267-282.

Ge, T., Chen, C.-Y., Ni, Y., Feng, Y.-C. A., & Smoller, J. W. (2019). Polygenic prediction via Bayesian regression and continuous shrinkage priors. Nature Communications, 10(1), 1776.